Pathways
Alzheimer Pathway.Pathway of Alzheimer’s Disease. Our upload genes are marked by red star. The genes in red are labeled by KEGG, and they are in our results. And these genes are ADAM metallopeptidase domain 10 (ADAM10), LDL receptor related protein 1 (LRP1), Amyloid beta precursor protein (APP), Apolipoprotein E (APOE), Beta-secretase 1 (BACE1), Cyclin dependent kinase 5 (CDK5), Microtubule associated protein tau (MAPT), Insulin degrading enzyme (IDE), Presenilin 1 (PSEN1), Presenilin 2 (PSEN2), Synuclein alpha (SNCA) and Tumor necrosis factor (TNF).
Amyotrophic lateral sclerosis (ALS) pathway.Our upload genes are marked by red star, these genes are catalase (CAT), superoxide dismutase 1, soluble (SOD1), translocase of outer mitochondrial membrane 40 (TOMM40), tumor necrosis factor (TNF).
Biosynthesis of amino acids pathway.Our upload genes in this pathway are in the list of gene, but they are not labeled in the map, and they are argininosuccinate lyase (ASL), citrate synthase (CS), cystathionine-beta-synthase (CBS), pyruvate carboxylase (PC), serine dehydratase (SDS), tyrosine aminotransferase (TAT).
Biosynthesis of antibiotics pathway.The pathway of our uploaded genes cannot be download, so this pathway is the total pathway of Biosynthesis of antibiotics in Kegg database. Our result genes in this pathway are in the list of gene, but they are not labeled in the map, and they are argininosuccinate lyase (ASL), catalase (CAT), citrate synthase (CS), cystathionine-beta-synthase (CBS), serine dehydratase (SDS), tyrosine aminotransferase (TAT).
Carbon metabolism pathway.Our upload genes in this pathway are in the list of gene, but they are not labeled in the map, and they are catalase (CAT), citrate synthase (CS), pyruvate carboxylase (PC), serine dehydratase (SDS).
Cocaine addiction pathway.Our upload genes are marked by red star, these genes are brain derived neurotrophic factor (BDNF), cyclin dependent kinase 5 (CDK5), monoamine oxidase A (MAOA).
Cysteine and methionine metabolism pathway.Our upload genes are marked by red star, these genes are cystathionine-beta-synthase (CBS), serine dehydratase (SDS), tyrosine aminotransferase (TAT).
Cytokine-cytokine receptor interaction pathway.Our upload genes in this pathway are in the list of gene, but they are not labeled in the map, and they are C-C motif chemokine receptor 5 (CCR5), CD40 molecule (CD40), MET proto-oncogene, receptor tyrosine kinase (MET), epidermal growth factor (EGF), Erythropoietin (EPO), tumor necrosis factor (TNF).
Glycine, serine and threonine metabolism pathway.Our upload genes are marked by red star, these genes are cystathionine-beta-synthase (CBS), monoamine oxidase A (MAOA), serine dehydratase (SDS).
Malaria pathway.Our upload genes are marked by red star, these genes are CD40 molecule (CD40), LDL receptor related protein 1 (LRP1). MET proto-oncogene, receptor tyrosine kinase (MET), tumor necrosis factor (TNF).
Nitrogen metabolism pathway.Our upload genes are marked by red star, these genes are carbonic anhydrase 3 (CA3), carbonic anhydrase I (CA1), carbonic anhydrase II (CA2).
Notch signaling pathway.Our upload genes are marked by red star, these genes are notch 3 (NOTCH 3), presenilin 1 (PSEN1), presenilin 2 (PSEN2).
| Term | Details | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | % | PValue | Pop Hits | Pop Total | Fold Enrichment | Bonferroni | Benjamini | FDR | |
| Alzheimer's disease | 12 | 0.049532 | 4.20E-07 | 178 | 7583 | 7.40 | 6.84E-05 | 6.84E-05 | 5.08E-04 |
| Biosynthesis of amino acids | 6 | 2.47E-02 | 4.99E-04 | 74 | 7583 | 8.91 | 7.81E-02 | 3.98E-02 | 6.02E-01 |
| Nitrogen metabolism | 3 | 1.24E-02 | 9.88E-03 | 17 | 7583 | 19.39 | 8.02E-01 | 4.17E-01 | 11.33 |
| Malaria | 4 | 1.65E-02 | 1.17E-02 | 53 | 7583 | 8.29 | 8.54E-01 | 3.82E-01 | 13.33 |
| Amyotrophic lateral sclerosis (ALS) | 4 | 1.65E-02 | 1.23E-02 | 54 | 7583 | 8.14 | 8.68E-01 | 3.33E-01 | 13.97 |
| Biosynthesis of antibiotics | 6 | 2.48E-02 | 3.69E-02 | 206 | 7583 | 3.20 | 9.98E-01 | 6.40E-01 | 36.62 |
| Cysteine and methionine metabolism | 3 | 1.24E-02 | 4.53E-02 | 38 | 7583 | 8.68 | 9.99E-01 | 6.40E-01 | 42.96 |
| Glycine, serine and threonine metabolism | 3 | 1.24E-02 | 5.19E-02 | 41 | 7583 | 8.04 | 1.00 | 6.63E-01 | 47.58 |
| Cytokine-cytokine receptor interaction | 6 | 2.48E-02 | 6.17E-02 | 238 | 7583 | 2.77 | 1.00 | 6.84E-01 | 53.75 |
| Notch signaling pathway | 3 | 1.24E-02 | 6.62E-02 | 47 | 7583 | 7.01 | 1.00 | 6.72E-01 | 56.36 |
| Cocaine addiction | 3 | 1.24E-02 | 7.12E-02 | 49 | 7583 | 6.73 | 1.00 | 6.65E-01 | 59.11 |
| Carbon metabolism | 4 | 1.65E-02 | 7.40E-02 | 109 | 7583 | 4.03 | 1.00 | 6.48E-01 | 60.61 |
